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Page 1
Polycomb deficiency drives a FOXP2-high aggressive state targetable by epigenetic inhibitors.
Chen F, Byrd AL, Liu J, Flight RM, DuCote TJ, Naughton KJ, Song X, Edgin AR, Lukyanchuk A, Dixon DT, Gosser CM, Esoe DP, Jayswal RD, Orkin SH, Moseley HNB, Wang C, Brainson CF. Chen F, et al. Among authors: brainson cf. Nat Commun. 2023 Jan 20;14(1):336. doi: 10.1038/s41467-023-35784-x. Nat Commun. 2023. PMID: 36670102 Free PMC article.
Dysregulated Polycomb Repressive Complex 2 contributes to chronic obstructive pulmonary disease by rewiring stem cell fate.
Byrd AL, Qu X, Lukyanchuk A, Liu J, Chen F, Naughton KJ, DuCote TJ, Song X, Bowman HC, Zhao Y, Edgin AR, Wang C, Liu J, Brainson CF. Byrd AL, et al. Among authors: brainson cf. Stem Cell Reports. 2023 Jan 10;18(1):289-304. doi: 10.1016/j.stemcr.2022.11.009. Epub 2022 Dec 15. Stem Cell Reports. 2023. PMID: 36525966 Free PMC article.
Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.
Zhang H, Fillmore Brainson C, Koyama S, Redig AJ, Chen T, Li S, Gupta M, Garcia-de-Alba C, Paschini M, Herter-Sprie GS, Lu G, Zhang X, Marsh BP, Tuminello SJ, Xu C, Chen Z, Wang X, Akbay EA, Zheng M, Palakurthi S, Sholl LM, Rustgi AK, Kwiatkowski DJ, Diehl JA, Bass AJ, Sharpless NE, Dranoff G, Hammerman PS, Ji H, Bardeesy N, Saur D, Watanabe H, Kim CF, Wong KK. Zhang H, et al. Among authors: fillmore brainson c. Nat Commun. 2017 Apr 7;8:14922. doi: 10.1038/ncomms14922. Nat Commun. 2017. PMID: 28387316 Free PMC article.
Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer.
Zhang H, Qi J, Reyes JM, Li L, Rao PK, Li F, Lin CY, Perry JA, Lawlor MA, Federation A, De Raedt T, Li YY, Liu Y, Duarte MA, Zhang Y, Herter-Sprie GS, Kikuchi E, Carretero J, Perou CM, Reibel JB, Paulk J, Bronson RT, Watanabe H, Brainson CF, Kim CF, Hammerman PS, Brown M, Cichowski K, Long H, Bradner JE, Wong KK. Zhang H, et al. Among authors: brainson cf. Cancer Discov. 2016 Sep;6(9):1006-21. doi: 10.1158/2159-8290.CD-16-0164. Epub 2016 Jun 16. Cancer Discov. 2016. PMID: 27312177 Free PMC article.
Erratum: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.
Zhang H, Brainson CF, Koyama S, Redig AJ, Chen T, Li S, Gupta M, Garcia-de-Alba C, Paschini M, Herter-Sprie GS, Lu G, Zhang X, Marsh BP, Tuminello SJ, Xu C, Chen Z, Wang X, Akbay EA, Zheng M, Palakurthi S, Sholl LM, Rustgi AK, Kwiatkowski DJ, Alan Diehl J, Bass AJ, Sharpless NE, Dranoff G, Hammerman PS, Ji H, Bardeesy N, Saur D, Watanabe H, Kim CF, Wong KK. Zhang H, et al. Among authors: brainson cf. Nat Commun. 2017 Jun 9;8:15901. doi: 10.1038/ncomms15901. Nat Commun. 2017. PMID: 28598439 Free PMC article.